BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex was approved as a therapy for strabismus in adults in December 1989. It is thought to work by lengthening the injected muscle while shortening the opposing muscle. The duration of effect is approximately three months. If necessary, the neurotoxin can be reinjected as long as the patient continues to respond and does not have a serious allergic reaction.1

During the administration of BOTOX® for the treatment of strabismus, retrobulbar hemorrhages sufficient to compromise retinal circulation have occurred from needle penetration into the orbit.

BOTOX® treatments may, on occasion, adversely affect muscles next to the injection site causing eyelid drooping or vertical deviation, especially if higher doses of BOTOX® are required as part of the treatment regimen. The treatments may also cause paralysis in one or more muscles outside the eyeball, causing spatial disorientation, double vision, or pastpointing.1

BOTOX® is indicated for the treatment of strabismus and blepharospasm associated with dystonia, including benign essential blepharospasm or VII nerve disorders in patients 12 years of age and above.

1. Botox® Consumers Web Site
2. Botox® Full Prescribing Information